ACNES · the numbers

Not rare. But structurally missed.

ACNES is often dismissed as an odd, rare diagnosis. The numbers say otherwise: it is common, it has been described for almost a hundred years, and yet people live with it for years before anyone recognises it. That is the trap.

How common it is

More common than you think

The figures vary by source, because without recognition there is no complete count either. But even the cautious estimates show this is not an exception. The figures below come from the situation in the Netherlands.

1 in 2,000

people develop ACNES each year, according to Dutch doctoral research. That is not a rarity.

~25,000

people in the Netherlands have ACNES as the cause of their chronic abdominal pain.

2 : 1

for every 2 patients with acute appendicitis, there is 1 patient in whom ACNES can be diagnosed.

That last comparison is telling. Every doctor recognises appendicitis immediately. ACNES, which occurs about half as often, often goes unnamed for years. Not because it is so rare, but because it is not on the radar.
The cost of missing it

What a missed diagnosis costs

A missed diagnosis is not free. Not for you, and not for the system. Research mapped the costs in the year before diagnosis (in the Netherlands).

€19,200 per patient

in largely avoidable care and productivity costs in the year before diagnosis. Think of scans, scopes, referrals and time off work: test after test that finds nothing, because the wrong thing is being examined.

"Test after test that finds nothing. Not because there is nothing, but because no one looks at the abdominal wall."

Why it gets missed

It is not in the patient, it is in the looking

ACNES falls out of view for reasons that have nothing to do with the severity of your complaint.

Unknown to doctors

The diagnosis comes about with difficulty, mainly because of unfamiliarity with this form of nerve pain, among both doctors and patients.

No conclusive test

There is no scan that proves ACNES with certainty. It requires targeted physical examination, and you have to think of it.

Organs first

With abdominal pain, the organs are examined first. Only when everything comes back negative does the abdominal wall sometimes come into view. Often far too late.

What the numbers do not tell

The years in between count for no one

Counted

What is visible

  • Patients who eventually get the diagnosis
  • Treatment results in specialised centres
  • The direct care costs of tests
Not counted

What stays invisible

  • Everyone who does not yet have a diagnosis and keeps searching
  • People who gave up and accepted the pain as "chronic and unexplained"
  • The mental toll of years of not being believed
  • Those who had the wrong treatment or surgery
Sources

Where these figures come from

1 in 2,000 per year and the €19,200 cost
Doctoral research by Tijmen van Assen (Máxima MC / SolviMáx), via Maastricht University. See the news article from SolviMáx (in Dutch).
25,000 people in the Netherlands
Patient information from Nij Smellinghe Hospital on ACNES as a cause of chronic abdominal pain. See nijsmellinghe.nl (in Dutch).
Ratio to appendicitis
ACNES symposium "Alles op een rij" (Eindhoven), via Sportgeneeskunde Nederland: for every 2 patients with acute appendicitis there is 1 with ACNES. See sportgeneeskunde.com (in Dutch).
Official guideline
There is a national guideline for the diagnosis and treatment of ACNES in the Netherlands. See the Dutch guidelines database (in Dutch).

🏎 Need help right now?

If there is immediate danger to yourself or someone else: call 112. Feeling low or having thoughts of suicide? In the Netherlands you can call or chat day and night with 113 Suicide Prevention via 0800-0113. Outside the Netherlands, contact your local emergency line.